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Isophoric News · Thursday, October 22, 2026

Health

Christina Applegate says her multiple sclerosis diagnosis was incorrect

By D. Marlowe · October 22, 2026 · First reported October 21, 2026 · Edited by C. Fletcher

Actor Christina Applegate said Tuesday that she was misdiagnosed with multiple sclerosis, NPR reported. She announced the diagnosis in 2021 and later retired from acting, according to NPR. MedPage Today's summary of its own report says she revealed that her doctor told her the diagnosis was incorrect and quotes her as saying "I'm back at square one." Michael Kornberg, a neurologist at Johns Hopkins University, told NPR that there is no single test for MS and that misdiagnosis rates cited in studies range from 5% to 20% depending on the clinic investigated.

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